In the config.py you must insert your database connection settings:

config = {
    ## Database connection settings
    # sqlite not supported yet!
    "dbTyp"             : "MySQLdb", # "sqlite"


# Instead of 'localhost' you must possibly use the domain name or IP
    "dbHost"            : 'localhost',


"dbDatabaseName"    : 'DatabaseName',
    "dbUserName"        : 'UserName',
    "dbPassword"        : 'Password',
    "dbTablePrefix"     : 'pylucid_', # No blanks may contain!
...
}

The other settings are explain in the config.py...

You can Browse the config.py file in our trac: http://pylucid.net/trac/browser/trunk/config.py